This tool will take you through current, open clinical trials in the UK and help you to understand which trials may be suitable for you. With any clinical trial you will need to be referred by your Health Care Specialist, always seek advice when considering clinical trials.

Further information can be found on our website under Clinical Trials and Novel Drugs or if you would like to speak to someone please call the Myeloma UK infoline on: 0800 980 3332

The Myeloma Trial Finder is intended only to provide information about clinical trials currently available in the UK. Trials included on Myeloma Trial Finder are not necessarily endorsed by Myeloma UK. Clinical trials involve inherent risks and any decision to participate, or not participate, in a clinical trial should be taken only after a careful assessment of the risks involved in it. Please speak to your haematologist if you are interested in taking part in a clinical trial. To the fullest extent permitted by law Myeloma UK excludes all liability howsoever arising (including negligence) as a consequence of, or in connection with, the use of information provided by Myeloma Trial Finder

There are currently 31 open trials. In 131 locations

What is a Clinical Trial?

Step 2: Choose a Trial

There are currently 31 open trials

Step 3: View Details

Trial Title:

Trial of Immunomodulatory Therapy in High Risk Solitary Bone Plasmacytoma (IDRIS)

Treatments:

Lenalidomide (Revlimid®)
Dexamethasone
Radiotherapy

Myeloma stage:

Bone Plasmacytoma

Trial phase:

III

Summary

Summary:

The aim of this trial is to determine whether taking lenalidomide and dexamethasone after radiotherapy is more effective at treating high risk solitary bone plasmacytoma than radiotherapy alone.

Locations

Locations:

Royal United Hospital, Bath;
Blackpool Victoria Hospital, Blackpool;
University Hospital of Wales, Cardiff;
Velindre Cancer Centre, Cardiff;
The Beatson Institute, Glasgow;
St James' Hospital, Leeds;
University College Hospital, London;
The Christie Hospital, Manchester;
Freeman Hospital, Newcastle;
Mount Vernon Cancer Centre, Northwood;
Royal Preston Hospital, Preston;
Salisbury District Hospital, Salisbury;
Southampton General Hospital, Southampton

Who can enter the study?

Who can enter the study?:

Patients with newly diagnosed solitary bone plasmacytoma.

What's involved?

What's involved?:

Patients are randomised to receive either lenalidomide and dexamethasone or no treatment after receiving radiotherapy to treat the solitary bone plasmacytoma.

Patients assigned to the treatment leg of the trial will receive lenalidomide on days 1-21 and dexamethasone on days 1, 8, 15  & 22 for up to 9 cycles.

Patients maybe required to attend outpatient clinics for regular check-ups and tests.

Clinical Information

Clinical Information
(for Medical Professionals):

The purpose of the phase III trial is to establish whether adjuvant therapy with lenalidomide and dexamethasone after radiotherapy can improve progression free survival in patients with high risk solitary bone plasmacytoma compared with radiotherapy only.

The investigators hope to demonstrate that adjuvant therapy with lenalidomide and dexamethasone prevents the development of multiple myeloma in patients with high risk solitary bone plasmacytoma.

For further information, click here.

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